| Unlockable | How to Unlock |
| Ronin Notoriety Reduced | Drug Traffickingf Level 3 (Hotel and Marina) |
| Pumped Up | Fight Club level 3 (Arena) |
| Pumped Up | Fight Club level 6 (Arena) |
| Sprint Increased | Insurance Fraud level 3 (Factories) |
| Sprint Increased (Unlimited) | Insurance Fraud level 6 (Factories) |
| Reduced bullet damage | Heli assault level 3 (Bario) |
| Health Regeneration 2x | Snatch level 3 (Chinatown) |
| Health Regeneration 3x | Snatch level 6 (Chinatown) |
| Brotherhood Melee | Complete Brotherhood Mission 6 |
| Ronin Melee | Complete Ronin Mission 6 |
| X2 Ultimax (Shotgun) | Drug Trafficking level 3 (Airport) |
| Kobra (Pistol) | Fuzz level 3 (Projects) |
| Unlimited Pistol Ammo | Fuzz level 6 (Projects) |
| Donnie's Vehicle | Complete Brotherhood mission 2 |
| Gang Customization Cars | 15% hoods conquered |
| Gang Customization Cars | 45% hoods conquered |
| The News Helicopter | Complete Sons of Samedi Mission 3 |
| Clothing Store Discount | Crowd Control level 3 (Suburbs) |
| Crib Customization Discount | Mayhem level 3 (Red Light) |
| Vehicle Delivery | Escort level 3 (Red Light) |
| Tobias | Complete Sons of Samedi Mission 3 |
| One Follower | Complete Prologue Mission 4 |
| Two Followers | 25% hoods conquered |
| Three Followers | 50% hoods conquered |
| Red Light Apartment Crib | Complete Prologue Mission 2 |
| Saints Hideout | Complete Prologue Mission 3 |
| Bodyguards and Ninjas | Game Progression |
| Police Notoriety Reduced | Complete FUZZ Level 3, Suburbs |
| Police Notoriety Reduced 2 | Complete FUZZ Level 6, Suburbs |
| Sons of Samedi Notoriety Reduced | Complete Escort Level 3, University |
| Demo Derby Vehicles | Complete Demo Derby Level 6 |
| Mechanic Discount | Complete Demo Derby Level 3 |
| Brotherhood Gang Cars | Complete Last Mission for the Brotherhood |
| Ronin Gang Cars | Complete Last Mission for the Ronin |
| Sons Of Samedi Gang Cars | Complete Last Mission for Sons Of Samedi |
| Sons Of Samedi Melee | Complete Mission "Bad Trip" |
| Infinite SMG Ammo | Complete "Snatch" Level 6 Downtown |
| Pepper Spray in Weapon Cache | Complete Crowd Control (Marina) lvl 3 |
| Chainsaw in Weapon Cache | Complete Crowd Control (Marina) lvl 6 |
| Kobra(Pistol) | Complete Fuzz Level 3(Projects) |
| Legal Lee | Beat 'Stilwater Prison Fight Club Level 3' |
| Troy | Beat 'Stilwater Prison Fight Club Level 6 |
| Buggy | Complete Truckyard Chop Shop list |
| Zombie Carlos | Call eye for an eye after you complete the brother hood story |
| 75% Mechanic Discount | Complete all 5 Chop Shop lists |
| Explosion Damage (-5%) | Level 3, Trail Blazing (Downtown) |
| Infinite Respect | Do activities to raise your respect past level 99, you will then have Infinite respect |
| Improved Weapon Accuracy 15% | Finish Septic Avenger Level 6, Suburbs |
| 5% Food and Liquor Store Discount | Beat 'Red Light Septic Avenger Level 3' |
| 15% Food and Liquor Store Discount | Beat 'Red Light Septic Avenger Level 6' |
| Septic Truck | Beat both of the Septic Avengers |
| Ronin Notority Reduced 2 | Beat 'Hotels & Marina Drug Trafficking Level 6' |
| Fire Fighter Suit | Complete both set of Trailblazing activities |
| Pimp Suit | Complete Ho-ing Diversion |
| Bandit | Do multiple car stunts to unlock |
| Johnny Gat | Complete final Ronin mission |
| Unlimited Rifle Ammo | Complete all 5 Hitman lists |
| Hand Grenades | 1 Hitman list complete |
| Satchel Charges | 3 Hitman lists complete |
| Infinite Shotgun Ammo | Complete Drug Trafficking level 6 (Airport) |
| Paintball Mask | Mugged 30 People |
| Pierce | Complete Ronin Storyline |
| Shaundi | Complete Sons of Samedi Storyline |
| Reduced Vehicle Damage | Insurance Fraud Level 3, Museum |
| Shock Paddles (Melee Weapon) | All Ambulance Levels |
| AR-50 XMAC Special | All Combat Tricks Completed |
| Ambulance | ll Ambulance Levels |
| Super Taxi | All Taxi Levels |
| Avenger Jacket | 3 Gold Stars in Gang Kills |
| Traffic Cone Hat | 3 Gold Stars in Vehicle Surfing |
| Zombie Mask | Complete Zombie Uprising |
| No damage from falling | Get a bull's eye in the base jumping diversion |
| Pimpcane | Pyramid Scheme |
| Akuji's Prototype Bike | Ronin Mission 11 |
| Brotherhood Melee | Brotherhood, Mission 6 |
| Health Regeneration (x2) | Snatch, Mission 3 (Chinatown) |
| Health Regeneration (x3) | Snatch, Mission 6 (Chinatown) |
| Improved Weapon Accuracy | Septic Avenger, Mission 3 (Suburbs) |
| Improved Weapon Accuracy II | Septic Avenger, Mission 6 (Suburbs) |
| Pumped Up | Fight Club, Mission 3 (Arena) |
| Pumped Up II | Fight Club, Mission 6 (Arena) |
| Reduced Bullet Damage | Heli Assault, Mission 3 (Bario) |
| Ronin Melee | Ronin, Mission 6 |
| Ronin Notoriety Reduced | Drug Trafficking, Mission 3 (Hotel and Marina) |
| Sons of Samedi Notoriety Reduced | Snatch, Mission 3 (University) |
| Sons of Samedi Notoriety Reduced II | Snatch, Mission 6 (University) |
| Sprint Increased | Insurance Fraud, Mission 3 (Factories) |
| Sprint Increased II | Insurance Fraud, Mission 6 (Factories) |
| Akuji’s Prototype Bike | Complete Ronin, Mission 11 |
| Bandit | Complete all of the driving stunts |
| Donnie’s Vehicle | Complete Brotherhood, Mission 2 |
| Gang Customization Cars | Conquer 15% of hoods |
| Gang Customization Cars II | Conquer 45% of hoods |
| Gang Customization Cars III | Conquer 65% of hoods |
| The General’s Bulldog | Complete Sons of Samedi, Mission 11 |
| Medical Helicopter | Complete Ronin, Mission 7 |
| News Helicopter | Complete Sons of Samedi, Mission 3 |
| Ronin Vehicles | Complete Ronin, Mission 11 |
| Saints Ambulance | Complete all ambulance missions |
| Saints Fire Truck | Complete all firefighter missions |
| Sons of Samedi Vehicles | Complete Sons of Samedi, Mission 11 |
| Tornado Attack Helicopter | Complete the final mission of the Ultor Epilogue |
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